M. Diem et al., Infrared spectroscopy of human cells and tissue. VIII. Strategies for analysis of infrared tissue mapping data and applications to liver tissue, BIOPOLYMERS, 57(5), 2000, pp. 282-290
Experimental and computational methods of infrared microspectroscopy (IRI-M
SP) and infrared spectral mapping (ISM) are presented. These methods are su
bsequently applied to the analysis of cirrhotic liver tissue. The sensitivi
ty of infrared spectral mapping toward spectral changes caused by disease w
ill be demonstrated. In addition, the excellent agreement between ISM data
and histopathological information will be discussed. (C) 2000 John Wiley &
Sons, Inc.