Paeonilide, a novel anti-PAF-active monoterpenoid-derived metabolite from Paeonia delavayi

Authors
Liu, JK Ma, YB Wu, DG Lu, Y Shen, ZQ Zheng, QT Chen, ZH
Citation
Jk. Liu et al., Paeonilide, a novel anti-PAF-active monoterpenoid-derived metabolite from Paeonia delavayi, BIOS BIOT B, 64(7), 2000, pp. 1511-1514
Citations number
9
Categorie Soggetti
Agricultural Chemistry","Biochemistry & Biophysics
Journal title
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
ISSN journal
09168451 → ACNP
Volume
64
Issue
7
Year of publication
2000
Pages
1511 - 1514
Database
ISI
SICI code
0916-8451(200007)64:7<1511:PANAMM>2.0.ZU;2-G
Abstract
A novel monoterpenoid-derived metabolite, paeonilide, was isolated from the roots of Paeonia delavayi. Its structure was established by a combination of spectroscopic and X-ray crystallographic analyses. It showed an anti-PAF effect with an IC50 value of ca. 8 mu g/ml.