Identification, determination and biological evaluation of novel styrene trimer in polystyrene container

Authors
Yamada, T Hirano, S Kobayashi, K Sakurai, T Takaki, I Tanaka, M Nagao, Y Azuma, Y Date, K Ohno, K Chiba, M Nobuhara, Y
Citation
T. Yamada et al., Identification, determination and biological evaluation of novel styrene trimer in polystyrene container, BUNSEKI KAG, 49(7), 2000, pp. 493-501
Citations number
5
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
BUNSEKI KAGAKU
ISSN journal
05251931 → ACNP
Volume
49
Issue
7
Year of publication
2000
Pages
493 - 501
Database
ISI
SICI code
0525-1931(200007)49:7<493:IDABEO>2.0.ZU;2-#
Abstract
The presence of unidentified styrene trimers (NST-12-1 and NST-12-2) was co nfirmed in the eluted substance of polystyrene. Both compounds were two dia stereomers of 1-phenyl-4- (2-phenylethyl) tetralin, which were proved to be the 1,4-cis (NST-12-1) and 1,4-trans (NST-12-2) configuration by instrumen tal analysis and chemical synthesis. The content and miglation of NST-12 in polystyrene products were determined by GC/MS (SIM). Furthermore, the endo crine-disrupting effects of NST-12 were tested by in vivo and in vitro assa ys. It appeared that NST-12 has no such effects.