Determination of the substituent distribution in O-sulfonylbutyl-(1 -> 4)-glucans

Citation
N. Rogmann et al., Determination of the substituent distribution in O-sulfonylbutyl-(1 -> 4)-glucans, CARBOHY RES, 327(3), 2000, pp. 275-285
Citations number
24
Categorie Soggetti
Agricultural Chemistry","Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
CARBOHYDRATE RESEARCH
ISSN journal
00086215 → ACNP
Volume
327
Issue
3
Year of publication
2000
Pages
275 - 285
Database
ISI
SICI code
0008-6215(20000724)327:3<275:DOTSDI>2.0.ZU;2-T
Abstract
A method has been developed to determine the distribution of substituents i n the glucose units of sulfonylbutylethers of cyclomaltoheptaose (beta-cycl odextrin). This method involves hydrolysis of the glucosidic linkages, perm ethylation, formation of sulfonylchlorides and subsequent transformation to the permethylated sulfonylfluoride derivatives. The latter were thermostab le and could be analyzed by GLC and identified by EI and CIMS. For confirma tion, the 2-, 3-, and 6-O-substituted standard compounds were independently synthesized and characterized by NMR and GLC-MS. (C) 2000 Elsevier Science Ltd. All rights reserved.