Efficient planar chiral 2 '-substituted 1,1 '-P,N-ferrocene ligands for the asymmetric Heck reaction: control of enantioselectivity and configurationby planar chiral substituent

Planar chiral 1,1'P,N-2'-substituted 2' substituted 1,1'-P,N-ferrocene deri vatives were efficient ligands for the Pd-catalyzed asymmetric Heck reactio n, in which 79-85% yields with high enantioselectivity (80-92%) were obtain ed within several hours; the enantioselectivity and the absolute configurat ion were controllable by changing the size of the planar chiral group and/o r configuration of planar chirality.