Sh. Cohen et al., Persistence of an endemic (toxigenic) isolate of Clostridium difficile in the environment of a general medicine ward, CLIN INF D, 30(6), 2000, pp. 952-954
The epidemiology of Clostridium difficile-associated diarrhea (CDAD) in an
endemic setting was investigated by use of DNA typing methods to determine
the strain identity of C. difficile isolates. Two predominant toxigenic clo
nes were found in the environment and accounted for 29.8% (type 1) and 15.5
% (type 2) of CDAD cases, respectively. In endemic settings, the environmen
t and cross-transmission may play a role in acquisition of CDAD.