Entamoeba histolytica/Entamoeba dispar infections in human immunodeficiency virus-infected patients in the United States

We describe the incidence of and laboratory and clinical characteristics as sociated with Entamoeba histolytica/Entamoeba dispar infection diagnosed in human immunodeficiency virus (HIV-infected persons enrolled in the Adult a nd Adolescent Spectrum of HIV Disease Project, From 1 January 1990 to 1 Jan uary 1998 (82,518 person-years of follow-up), 111 patients (98% men) were d iagnosed with E. histolytica/E. dispar infection. Among HIV-infected patien ts in the United States, the incidence of diagnosed E. histolytica disease is low (13.5 cases per 10,000 person-years [95% confidence interval, 7.7-22 .2], with diagnosis most common in those patients exposed to HIV through ma le-male sex.