The presence of the ossific nucleus and its role in reducing the risk of is
chemic necrosis in developmental dysplasia of the hip remains a matter of c
ontroversy. Ischemic necrosis of the preosseous capital femoral epiphysis,
defined as chondronecrosis, was evaluated in a rabbit model. Histologic evi
dence of chondronecrosis after casting in maximum abduction was greater in
1-day-old New Zealand White rabbits before the radiographic appearance of t
he ossific nucleus, compared with 16-day-old New Zealand White rabbits with
an ossific nucleus already present. This preliminary study supports the hy
pothesis that the ossific nucleus may decrease the risk of intracapsular co
mpressive ischemic injury to the developing capital femoral epiphysis in a
rabbit model.