NMR studies of a neurotoxin (candoxin) from Bungarus candidus - Presence of a predominantly beta-sheet structure

Authors
Parvathy, VR Chary, KVR Kini, RM Govil, G
Citation
Vr. Parvathy et al., NMR studies of a neurotoxin (candoxin) from Bungarus candidus - Presence of a predominantly beta-sheet structure, CURRENT SCI, 79(2), 2000, pp. 219-222
Citations number
19
Categorie Soggetti
Multidisciplinary,Multidisciplinary
Journal title
CURRENT SCIENCE
ISSN journal
00113891 → ACNP
Volume
79
Issue
2
Year of publication
2000
Pages
219 - 222
Database
ISI
SICI code
0011-3891(20000725)79:2<219:NSOAN(>2.0.ZU;2-8
Abstract
Complete sequence-specific H-1 resonance assignments of a neurotoxin, cando xin, from Bungarus candidus has been reported. Qualitative interpretation o f the nOes, chemical shift indices and deuterium exchange rates indicate a highly ordered and rigid conformation for this protein with an extended con formation for more than 50% of the residues and the complete absence of alp ha-helical segments.