Specific role of postprandial glucose peaks on HbA1c and angiopathy

Citation
A. Avignon et L. Monnier, Specific role of postprandial glucose peaks on HbA1c and angiopathy, DIABETE MET, 26, 2000, pp. 12-15
Citations number
7
Categorie Soggetti
Endocrinology, Nutrition & Metabolism
Journal title
DIABETES & METABOLISM
ISSN journal
12623636 → ACNP
Volume
26
Year of publication
2000
Supplement
2
Pages
12 - 15
Database
ISI
SICI code
1262-3636(200006)26:<12:SROPGP>2.0.ZU;2-O
Abstract
Most studies argue for a strong relation between postprandial blood glucose and cardiovascular risk. Thus the DIS study establishes a significant link between postprandial glucose and the incidence of myocardial infarction as well as the occurrence of death. The DECODE study shows that identifying i ndividuals at risk for death can be done through OGTT 2 h blood glucose, wh atever fasting glycemia is. Kumamoto study shows a reduction in microangiop athic complications when postprandial blood glucose is corrected by a multi injection protocol. Finally, a study conducted in Montpellier shows that po stprandial blood glucose better reflects the overall diabetes control than fasting glycemia. Altogether, these data suggest that managing postprandial blood glucose is essential for the prevention of vascular outcome in diabe tic patients.