The lateral periodontal cyst (LPC) is a relatively uncommon but widely reco
gnized odontogenic cyst of developmental origin. It is found mostly in adul
ts and has no sex predilection. LPC is usually discovered during routine ra
diographic examination, is located mainly between the roots of vital mandib
ular canines and premolars, and seldom causes pain or other clinical sympto
ms. The defect appears on radiographs as a round or teardrop-shaped, well c
ircumscribed radiolucency. Due to its location it can easily be misdiagnose
d as a lesion of endodontic origin. In this paper, two cases of lateral per
iodontal cysts are presented. In the first case, the patient (woman, 62 yea
rs old) complained of an asymptomatic gingival swelling in the region betwe
en the right maxillary canine and premolar. The radiographic examination re
vealed a well circumscribed radiolucency with a radiopaque margin between t
he roots of the canine and premolar. The adjacent teeth had vital pulp Surg
ical enucleation of the lesion was performed and the histological examinati
on revealed that die lesion was a "lateral periodontal cyst of developmenta
l origin". In the second case, the patient (woman, 44 years old) compained
of a swelling in the area of tooth 32. During radiographic examination a we
ll circumscribed radiolucency between the roots of the lateral incisor and
the canine was discovered. Surgical enucleation of the lesion was performed
and the histological examination revealed that the lesion was a "lateral p
eriodontal cyst of developmental origin".