Prognostic significance of tissue DF3 antigen and CA15-3 tumor marker in primary breast cancer

Authors
Dimas, C Fragos-Plemenos, M Gennatas, C Kouskouni, E Kondi-Paphitis, A
Citation
C. Dimas et al., Prognostic significance of tissue DF3 antigen and CA15-3 tumor marker in primary breast cancer, EUR J GYN O, 21(3), 2000, pp. 278-281
Citations number
10
Categorie Soggetti
Reproductive Medicine
Journal title
EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY
ISSN journal
03922936 → ACNP
Volume
21
Issue
3
Year of publication
2000
Pages
278 - 281
Database
ISI
SICI code
0392-2936(2000)21:3<278:PSOTDA>2.0.ZU;2-1
Abstract
The specific monoclonal antibody, DF3, for breast cancer and the correspond ing tumor marker CA15-3 were evaluated in 108 patients with primary cancer of the breast. These antigens correlated poorly with the known prognostic p arameters. Elevated CA153 serum values were associated with the cytoplasmic distribution of the DF3 antigen in the cell. The DF3 distribution pattern and the CA15-3 serum values had prognostic significance for disease-free in terval.