Effect of adjuvant chemotherapy using pirarubicin, cisplatin, and etoposide (PEP) for stage IVB endometrial carcinoma: A case report

Prognosis of patients with stage IVB endometrial adenocarcinoma is quite po or. Combination therapy of radiation with surgery or chemotherapy is a comm on therapy for advanced endometrial cancers. However, radiation therapy is effective only for localized cancel, and the chemotherapeutic effect on sta ge IVB endometrial cancers is very low. Wt: present a patient with stage IV B endometrial adenocarcinoma, whose tumor was not resected completely at th e first surgery. She showed a remarkable response to a PEP (pirarubicin, et oposide, cisplatin) regimen and has survived without disease over 8 years. This case suggests that reduction surgery following FEP therapy is a new th erapeutic modality for stage IVB endometrial carcinoma.