The echocardiographic findings of hypertrophic cardiomyopathy (HCM) are ver
y similar to those of cardiac amyloidosis. A 76-year-old Japanese man was a
dmitted for treatment of early stage gastric cancer in July 1996, His elect
rocardiogram indicated left ventricular hypertrophy and echocardiography sh
owed left ventricular hypertrophy with asymmetric septal hypertrophy. He wa
s re-admitted complaining of dyspnea on effort and pretibial edema in Octob
er 1998. The amplitude of QRS complex on electrocardiogram was decreased. E
chocardiogram showed left ventricular wall thickening with granular sparkli
ng. He was diagnosed as HCM with cardiac amyloidosis.