T. Abe et al., A patient with cyclic neutropenia complicated by severe persistent neutropenia successfully delivered a healthy baby, INTERN MED, 39(8), 2000, pp. 663-666
We describe a 24-year-old pregnant woman complicated by cyclic neutropenia
(CN), who was successfully treated with granulocyte-colony stimulating fact
or (G-CSF), Her white blood cell (WBC) and neutrophil count fluctuated from
2,600 to 4,600/mu l, and 26 to 2,530/mu l, respectively. The peak neutroph
il count gradually decreased as pregnancy advanced, resulting In the disapp
earance of its cyclicity. At 39 weeks of pregnancy when the neutrophil coun
t became 84/mu l, the patient was started on G-CSF and her neutrophil count
Increased to 1,550/mu l on the fourth day after delivery. She delivered a
healthy baby without any complications at 39 weeks of pregnancy.