Mapping of the N terminus of the Schistosoma mansoni tegumental antigen Sm15 to its predicted precursor protein

Authors
Werkhauser, RP De Simone, SG Xavier, E Montenegro, SML Abath, FGC
Citation
Rp. Werkhauser et al., Mapping of the N terminus of the Schistosoma mansoni tegumental antigen Sm15 to its predicted precursor protein, INT J PARAS, 30(7), 2000, pp. 859-861
Citations number
7
Categorie Soggetti
Biology,Microbiology
Journal title
INTERNATIONAL JOURNAL FOR PARASITOLOGY
ISSN journal
00207519 → ACNP
Volume
30
Issue
7
Year of publication
2000
Pages
859 - 861
Database
ISI
SICI code
0020-7519(200006)30:7<859:MOTNTO>2.0.ZU;2-Y
Abstract
Sm15 is a major Schistosoma mansoni 15 kDa tegumental antigen, resulting fr om the proteolytic processing of a larger precursor. The amino terminus of Sm15 was identified by direct amino acid sequencing, and the antigen was te ntatively mapped to the segment spanning amino acids 362-497 of the precurs or. This will allow subsequent studies to elucidate the possible immunologi cal role of proteolytic processing in schistosomiasis. (C) 2000 Australian Society for Parasitology Inc. Published by Elsevier Science Ltd. All rights reserved.