Ys. Lee et al., AN EFFICIENT SYNTHESIS OF 3-(E)-HYDROXYPROPENYL CEPHEM DERIVATIVES, KEY INTERMEDIATES FOR 3-(E)-AMMONIOPROPENYLCEPHALOSPORIN ANTIBIOTICS, Archives of pharmacal research, 20(3), 1997, pp. 288-290
An efficient synthesis of 3-(E)-hydroxy- and 3-(E)-acetoxypropenylceph
em derivatives, key intermediates for the synthesis of 3-(E)-propenylc
ephalosporins was achieved via Stille coupling reaction of 3-trifloxyc
ephem with 3-(E)-tributylstannylallylic alcohol.