3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) transferase of Legionella pneumophila transfers two Kdo residues to a structurally different lipid a precursor of Escherichia coli

Authors
Brabetz, N Schirmer, CE Brade, H
Citation
N. Brabetz et al., 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) transferase of Legionella pneumophila transfers two Kdo residues to a structurally different lipid a precursor of Escherichia coli, J BACT, 182(16), 2000, pp. 4654-4657
Citations number
26
Categorie Soggetti
Microbiology
Journal title
JOURNAL OF BACTERIOLOGY
ISSN journal
00219193 → ACNP
Volume
182
Issue
16
Year of publication
2000
Pages
4654 - 4657
Database
ISI
SICI code
0021-9193(200008)182:16<4654:3A(TOL>2.0.ZU;2-L
Abstract
The 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) transferase gene of Legionell a pneumophila was cloned and sequenced. Despite remarkable structural diffe rences in lipid A, the gene complemented a corresponding Escherichia coli m utant and was shown to encode a bifunctional enzyme which transferred 2 Kdo residues to a lipid A acceptor of E. coli.