ACTIVATION OF CARBOXYLIC-ACIDS BY PYROCAR BONATES - SYNTHESIS OF ALKYLAMIDES OF N-PROTECTED AMINO-ACIDS

Alkylamides of amino acids were prepared with high yields via activati on of N-protected amino acids by di-tert-pyrocarbonate-pyridine reagen t in the presence of alkylamine hydrochlorides and potassium hydrocarb onate.