Bioassay-guided fractionation of the EtOAc extract of a marine Bacillus sp.
Sc026 culture broth has led to the isolation of the known compound, macrol
actin F (1), together with two new compounds, 7-O-succinyl macrolactin F (2
) and 7-O-succinyl macrolactin A (3). The chemical structures of 1-3 were e
lucidated on the basis of spectral data analyses and literature data compar
ison. Compounds 1-3 exhibited antibacterial activity against Bacillus subti
lis and Staphylococcus aureus.