New macrolactins from a marine Bacillus sp Sc026

Citation
C. Jaruchoktaweechai et al., New macrolactins from a marine Bacillus sp Sc026, J NAT PROD, 63(7), 2000, pp. 984-986
Citations number
12
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
7
Year of publication
2000
Pages
984 - 986
Database
ISI
SICI code
0163-3864(200007)63:7<984:NMFAMB>2.0.ZU;2-R
Abstract
Bioassay-guided fractionation of the EtOAc extract of a marine Bacillus sp. Sc026 culture broth has led to the isolation of the known compound, macrol actin F (1), together with two new compounds, 7-O-succinyl macrolactin F (2 ) and 7-O-succinyl macrolactin A (3). The chemical structures of 1-3 were e lucidated on the basis of spectral data analyses and literature data compar ison. Compounds 1-3 exhibited antibacterial activity against Bacillus subti lis and Staphylococcus aureus.