Cerebellar cortical abiotrophy in a beagle

A beagle puppy was presented with clinical signs indicative of a cerebellar disease. Histopathological evaluation of the cerebellum revealed a diffuse degenerative cortical lesion. The clinical history and the histopathologic al findings are consistent with a neonatal cerebellar abiotrophy. Furthermo re, the breeding history supports the hypothesis of an inherited genetic di sorder that is, most likely, an autosomal recessive trait.