Using an epidemiological sample of adolescents, this study examined associa
tions between the acceptability of potential sex partners and psychiatric s
tatus. Method: Subjects aged 14 to 17 years (N = 161) from the Columbia sit
e of the National institute of Mental Health (NIMH) Methods for the Epidemi
ology of Child and Adolescent Mental Disorders (MECA) Study were grouped ac
cording to their responses about the acceptability of youths their age havi
ng sex with partners of (1) the opposite sex, (2) neither sex, and (3) eith
er sex. Youths endorsing either sex were compared with youths endorsing the
other two types of partners according to psychiatric indicators obtained f
rom the Diagnostic Interview Schedule for Children Version 2.3. Results: Hi
gher-than-expected proportions of male and female youths endorsed sex partn
ers of either sex as potentially acceptable for peers. Youths who did so ab
used substances and used mental health services more than peers but did not
differ in rates of suicidal ideation or attempts. Males endorsing either s
ex also had higher rates of mood disorders and, compared with males endorsi
ng only the opposite sex. a higher intelligence level. Conclusions: Attitud
es about the potential acceptability of sex partners for peers are associat
ed with psychiatric morbidity and mental health service use in the responde
nt as well as with intelligence level in males. Youths who endorsed potenti
al sex partners of either sex. especially males, appear to be at higher ris
k for multiple psychiatric problems.