A new statistical parametric model of carcinogenesis is proposed. The focus
is on tumor latency times. The model makes use of extreme value theory fol
lowing the line initially explored by Pike [1] and further developed by Kle
banov et al. [2]. In this paper, we make the first attempt to take account
of the interdependence between the cells in an initiated tissue developing
into a malignant tumor. (C) 2000 Elsevier Science Ltd. All rights reserved.