T. Orth et al., Acute mesenteric infarction in a 46-year-old male patient with primary antiphospholipid-antibody syndrome, MED KLIN, 95(7), 2000, pp. 409-412
Background: The antiphospholipid-antibody syndrome (APS) is a thrombophilic
disorder, in which venous and arterial thrombosis can occur. We report the
rare case of a patient with mesenteric infarction due to primary APS.
Case Report: A 46-year-old male patient was admitted to the hospital becaus
e of severe abdominal pain. A laparotomy was performed and revealed infarct
ion of a jejunal loop which was resected. At pathohistological examination
mesenteric artery infarction was found. Preoperatively prolonged partial th
romboplastin time led to coagulation analysis. Lupus anticoagulant and anti
cardiolipin antibodies were found.
Treatment: The diagnosis of primary APS was made and the patient was treate
d with aspirin (100 mg/day) and low molecular weight heparin (2.500 IE/day)
permanently. Eighteen months after mesenteric infarction the patient is fr
ee of further thromboembolic events.