Synthesis of structurally related purines: Benzimidazo[1,2-a]pyridines, benzimidazo-[1,2-c]pyrimidines, and pyrazolo-[1,5-a]pyrimidines

Authors
Elgemeie, GH Metwally, NH
Citation
Gh. Elgemeie et Nh. Metwally, Synthesis of structurally related purines: Benzimidazo[1,2-a]pyridines, benzimidazo-[1,2-c]pyrimidines, and pyrazolo-[1,5-a]pyrimidines, MONATS CHEM, 131(7), 2000, pp. 779-785
Citations number
12
Categorie Soggetti
Chemistry
Journal title
MONATSHEFTE FUR CHEMIE
ISSN journal
00269247 → ACNP
Volume
131
Issue
7
Year of publication
2000
Pages
779 - 785
Database
ISI
SICI code
0026-9247(200007)131:7<779:SOSRPB>2.0.ZU;2-D
Abstract
Reactions of sodium salts of 3-hydroxymethylene-2-alkanones with 2-cyanomet hylbenzimidazole afforded benzimidazo[1,2-a]pyridines. Analogues reactions with 2-aminobenzimidazole and 5-aminopyrazoles afforded benzimidazo[1.2-c]p yrimidines and pyrazolo[1,5-a]pyrimidines.