Synthesis and hemolytic properties of glycyrrhetic acid glycosides

Authors
Ullah, N Seebacher, W Weis, R Jurenitsch, J Rauchensteiner, K Haslinger, E
Citation
N. Ullah et al., Synthesis and hemolytic properties of glycyrrhetic acid glycosides, MONATS CHEM, 131(7), 2000, pp. 787-794
Citations number
15
Categorie Soggetti
Chemistry
Journal title
MONATSHEFTE FUR CHEMIE
ISSN journal
00269247 → ACNP
Volume
131
Issue
7
Year of publication
2000
Pages
787 - 794
Database
ISI
SICI code
0026-9247(200007)131:7<787:SAHPOG>2.0.ZU;2-K
Abstract
The synthesis of monodesmosidic glycyrrhetic acid disaccharides via its dip henylmethyl ester is described. Their hemolytic activity is lower as compar ed to the corresponding oleanolic acid disaccharides. The influence of the structure of the aglycon on the hemolytic activity is discussed.