We determined the sensitivity of computed tomography and color duplex ultra
sonography in the detection and characterization of vascular complications
in acute pancreatitis. The relationship of these complications with the eti
ology and activity of the disease was assessed. In a prospective study, 189
patients with acute pancreatitis seen in the Department of Gastroenterolog
y, Charite Hospital in Berlin over a period of 38 months underwent color du
plex ultrasonography every second day for 3 weeks and thereafter at least o
nce a week for 2 months. Dynamic computed tomography was performed within 7
2 hours after admission, and follow-up computed tomography scans were obtai
ned. In 45 patients (23%), at least temporary thromboses of portal venous v
essels were demonstrated by color duplex ultrasonography. The incidence of
venous thromboses was 30% in severe acute pancreatitis with fluid collectio
ns without necroses and 57% in necrotizing pancreatitis. In 27 of those 45
patients, a formation of collaterals was documented. In 13 patients, arteri
al pseudoaneurysms were demonstrated. Vascular complications were significa
ntly more frequent in alcohol-induced than in gallstone-induced pancreatiti
s. Only 62% of all sonographically diagnosed thromboses and only 32% of all
collaterals were demonstrated by computed tomography. The prevalence of va
scular complications in acute pancreatitis was much higher as suspected. Th
e risk of gastrointestinal bleeding was lower than previously reported. Col
or duplex sonography is the method of choice for the detection of vascular
complications in acute pancreatitis.