Papillary cystic tumor of the pancreas coexisting with hairy cell leukemia

The coexistence of a pancreatic papillary cystic tumor with hairy cell leuk emia is reported, To the best of our knowledge this association has never b een published. A 41-year-old man diagnosed with hairy cell leukemia develop ed a second malignancy that corresponded to a papillary cystic pancreatic t umor. The patient underwent splenectomy and a tumoral surgical resection, a nd is currently well at 21 months followup. A pathogenetic relationship bet ween the two malignancies was not demonstrated. Hairy cell leukemia has bee n reported to be associated to a great number of different second malignanc ies. In contrast, only two papillary cystic tumors of the pancreas have bee n described associated to a second neoplasm, a papillary thyroid carcinoma and a colonic carcinoma, This unusual benign or low-grade malignant pancrea tic tumor more commonly occurs in the tail of the pancreas of young women. We want to stress the unusual presentation of this pancreatic tumor affecti ng the head of the gland in a male patient as well as its coexistence with a hairy cell leukemia.