Effect of cellular mobility on immune response

Mobility of cell types in our HIV immune response model is subject to an in trinsic mobility and an explicit directed mobility, which is governed by P- mob We investigate how restricting the explicit mobility, while maintaining the innate mobility of a viral-infected cell, affects the model's results. We find that increasing the explicit mobility of the immune system cells l eads to viral dominance for certain levels of viral mutation. We conclude t hat increasing immune system cellular mobility indirectly increases the vir us' inherent mobility. (C) 2000 Elsevier Science B.V. All rights reserved.