Objective. The aim of the present study was to estimate the prevalence of d
ental fluorosis in primary dentition of a San Luis Potosi children populati
on, and its association to fluoride concentration in drinking water and uri
ne. An additional objective was, to develop, validate, and test a specific
index for dental fluorosis in primary dentition. Material and methods. From
May 1997, to January 1999, we conducted a cross-sectional study to assess
the prevalence of dental fluorosis in primary dentition. Study subjects wer
e 100 children aged 3-6 years, selected at random from three kindergartens
in three risk areas of San Luis Potosi. The specific index of dental fluoro
sis for primary dentition (Dental Fluorosis for Primary Dentition Index-DFP
DI) was validated by estimating fluoride concentrations in enamel of teeth
with and without dental fluorosis. The Kruskal-Wallis test was used to asse
ss the association between fluoride concentrations in drinking water and ur
ine,with dental fluorosis; the association between risk area and dental flu
orosis was assessed with the Mantel-Haenszel chi(2) test. Results. The prev
alence of dental fluorosis in primary dentition was 78%; primary molars wer
e most affected in both maxillae and the predominant color was a non-glossy
white appearance. We found a strong direct correlation (r=0.93) between fl
uoride concentrations in primary teeth and the DFPDI. Associations were fou
nd between fluoride concentrations of drinking water and urine, with dental
fluorosis (Kruskal-Wallis p=0.00001), and between risk area and dental flu
orosis (Mantel-Haenszel chi(2)p=0.00001). Conclusions. DFPDI allowed adequa
te identification and grading of dental fluorosis in primary dentition. It
is important to detect the initial toxic effects of fluoride exposure to pr
edict dental fluorosis in permanent dentition and skeletal fluorosis.