Asymmetric hydrogenations of diketopiperazines

Authors
Leeming, P Fronczek, FR Ager, DJ Laneman, SA
Citation
P. Leeming et al., Asymmetric hydrogenations of diketopiperazines, TOP CATAL, 13(3), 2000, pp. 175-177
Citations number
18
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
TOPICS IN CATALYSIS
ISSN journal
10225528 → ACNP
Volume
13
Issue
3
Year of publication
2000
Pages
175 - 177
Database
ISI
SICI code
1022-5528(2000)13:3<175:AHOD>2.0.ZU;2-8
Abstract
The dehydrodiketopiperazines 6 undergo face selective hydrogenation with a 5% palladium on carbon catalyst to give the diketopiperazines 7 in high yie ld with excellent diastereoisomeric ratios (>97%).