Enantio-differentiating hydrogenation of aromatic beta-ketoesters over tartaric acid-modified Raney nickel

Authors
Nakagawa, S Tai, A Okuyama, T Sugimura, T
Citation
S. Nakagawa et al., Enantio-differentiating hydrogenation of aromatic beta-ketoesters over tartaric acid-modified Raney nickel, TOP CATAL, 13(3), 2000, pp. 187-189
Citations number
10
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
TOPICS IN CATALYSIS
ISSN journal
10225528 → ACNP
Volume
13
Issue
3
Year of publication
2000
Pages
187 - 189
Database
ISI
SICI code
1022-5528(2000)13:3<187:EHOABO>2.0.ZU;2-#
Abstract
The optical yields of the enantio-differentiating hydrogenation of aromatic beta-ketoesters over tartaric acid-modified Raney nickel were found to be lower than those of aliphatic beta-ketoesters when the aromatic group is co njugated to the ketone moiety. The reason for the reduced optical yield is due to the lower intrinsic enantio-differentiation compared to the aliphati c substrate.