Ms. Al-thebeiti, An expeditious procedure for the synthesis of fused imidazol[1,2-c]pyrimido[4 ',5 ': 6,5]pyrano[3,2-h]quinolines, AFINIDAD, 57(487), 2000, pp. 211-216
A series of imidazo[1,2-c]pyrimido[4',5':6,5]pyrano[3,2-h]quinolines have b
een prepared from 2-amino-3-cyano-4-aryl-6-dimethylaminosulfonyl-4H- pyrano
[3,2-h]quinolines (1a,b) via reactions of 1a,b with ethylenediamine and cyc
lization of the resulting intermediates 2a,b with ortho ester, aldehydes an
d ketones.