Thrombotic thrombocytopenic purpura in pulmonary-renal syndromes

Thrombotic thrombocytopenic purpura pathologically consists of a thrombotic microangiopathy that classically spares lung tissues. We describe a case o f TTP that presented as a pulmonary-renal syndrome. In reviewing the intern ational literature, pulmonary involvement is not as rare as once was though t, and the diagnosis of TTP should be considered in the differential diagno sis of pulmonary-renal syndromes. (C) 2000 Wiley-Liss, Inc.