Several authors have proposed the use of statistical process control charti
ng methods for the surveillance of endemic rates of nosocomial infections.
The principal goal of such a charting program is to recognize any increase
of the endemic rate to an epidemic rare as soon as possible after the chang
e occurs. However, many of the statistical process control charting methods
that have been proposed are based on classical charting principles that ar
e effective largely for processes for which sufficient historical data are
available. These methods require that a fairly large data set, taken while
the infection rate was stable at a low endemic value, must be available to
begin the charting process. These data are used both to confirm the appropr
iateness of the probability distribution and to make a control chart for th
e infection process based on the distribution. However, such data sets are
often not available. The purpose of this article is to inform and demonstra
te to readers that recent research in statistics has developed modem statis
tical process control methods that can be used effectively with or without
such prior data. These methods make possible much more effective nosocomial
infection surveillance programs that will give timely warnings of the onse
ts of epidemics or evidence of the effectiveness of infection control initi
atives. These warnings will permit earlier correction initiatives and thus
avoid much liability.