Rhegmatogenous retinal detachment in retinoblastoma patients undergoing chemoreduction and cryotherapy

PURPOSE: To report the development of rhegmatogenous retinal detachment, wi th the retinal break adjacent to a cryotherapy scar, in three patients unde rgoing systemic chemotherapy for intraocular retinoblastoma. METHOD: Case series. RESULTS: Three patients with intraocular retinoblastoma were referred after poor response to systemic chemotherapy and local cryotherapy; three eyes o f these three patients were noted to have rhegmatogenous retinal detachment and active retinoblastoma, with retinal breaks adjacent to cryotherapy sca rs. CONCLUSION: Rhegmatogenous retinal detachment may result from retinal necro sis associated with cryotherapy in the setting of intraocular retinoblastom a treated with systemic chemotherapy and local cryotherapy. (C) 2000 by Els evier Science Inc. All rights reserved.