Background: The intubating laryngeal mask ah-way (ILMA) is designed to faci
litate blind tracheal intubation, The effect of a muscle relaxant on the ab
ility to perform tracheal intubation through the ILMA device has not been p
reviously evaluated. This randomized, double-blind, placebo-controlled stud
y was designed to evaluate rocuronium, 0.2 or 0.4 mg/kg administered intrav
enously, on the success rate and incidence of complications associated with
ILMA-assisted tracheal intubation,
Methods: A total of 75 healthy patients were induced with propofol 2 mg/kg
and fentanyl 1 mu g/kg intravenously. After insertion of the ILMA device, p
atients were administered either saline, rocuronium 0.2 mg/kg, or rocuroniu
m 0.4 mg/kg in a total volume of 5 mi. At 90 s after administration of the
study drug, tracheal intubation was attempted using a disposable polyvinyl
tube. If unsuccessful, a reusable silicone tube was tried. In addition to r
ecording the time and number of attempts required to secure the airway, the
incidence of complications during placement of the tracheal tube and remov
al of the ILMA were noted.
Results: Tracheal intubation was successful in. 76-96% of the patients. The
overall success rates and times required to secure the airway were similar
in all three treatment groups. The high-dose rocuronium group experienced
less patient movement (8 vs. 28 and 48%) and coughing (12 vs. 20 and 52%) t
han the low-dose rocuronium and saline groups, respectively. Use of rocuron
ium was also associated with a dose-related decrease in the requirement for
supplemental bolus doses of propofol during intubation and removal of the
ILMA device.
Conclusions: Use of rocuronium did not significantly improve the success ra
te in performing tracheal intubation through the ILMA. However, it produced
dose-related decreases in coughing and movement after tracheal intubation
and reduced difficulties associated with removal of the ILMA device.