The records of 138 patients (222 hands) who had been evaluated by preoperat
ive nerve conduction study (NCS) and consecutive self-administered question
naires were analyzed to determine diagnostic relations in carpal tunnel syn
drome, Hands were categorized into six grades (extreme, severe, moderate, m
ild, minimal, and negative) according to the three modalities: the NCS data
of the median sensory nerve, Symptom Severity Scale score, and Functional
Status Scale score. The authors evaluated the correlation, independence, ho
mogeneity, and association among parameters, and found the following: (1) t
he NCS data correlated more significantly (p < 0.05) and was associated mor
e linearly with Symptom Severity Scale score than the Functional Status Sca
le score; (2) the choice of modality exerted an influence on grading severi
ties, thus grades varied according to the modalities; and (3) the distribut
ion of patients was not homogenous; there were more extremes in NCS, and mo
re severe scores on the Symptom Severity Scale. Patients rated as one homog
eneous severity by NCS data may be interpreted into different severities (f
rom negative to extreme) by self-administered questionnaires and vice versa
.