Efficacy evaluation of lasalocid plus roxarsone combination medication with different geographic field strains of Eimeria acervulina

Performance of broiler chickens medicated with lasalocid alone (at 125 ppm) or in combination with roxarsone (at 50 ppm) was evaluated in battery and floorpen trials after challenge with geographically different field strains of coccidia containing predominately the upper intestinal species Eimeria acervulina. No significant difference in bird performance measured at 6 day s postinfection (PI) was observed between lasalocid plus roxarsone-medicate d (L+RM) or lasalocid-medicated (LM) birds challenged in separate battery t rials with mixed-species inocula from Alabama or Georgia containing 92% or 88% E. acervulina, respectively. In contrast, L+RM birds challenged in anot her battery trial with a Louisiana mixed-species inoculum containing 92% E. acervulina showed significant reduction in average weight gain at 6 days P I compared with LM-challenged birds. A floorpen trial done with the same Lo uisiana inoculum showed significant reduction in average bird weight gain a t 27 and 35 days of age (6 and 14 days PI) for L+RM-challenged birds compar ed with both unmedicated-nonchallenged (UMNC) control and LM-challenged bir ds. The LM+R groups were significantly lower in average bird weight at 27 d ays of age than the unmedicated-challenged controls. Feed conversions (FCs) for L+RM birds were significantly higher than those for the UMNC control b irds during time of challenge (21-27 days of age) and for the 1-to-27-day-o f-age time period. No significant difference in FC was seen between the UMN C and LM groups. Results of this study showed that performance of broiler b irds medicated with lasalocid plus roxarsone could vary for geographically different mixed-species challenge inocula that contained predominately E. a cervulina.