Biotechnological methods can be used for cryptography. Here two different c
ryptographic approaches based on DNA binary strands ale shown. The first ap
proach shows how DNA binary strands can be used for steganography, a techni
que of encryption by information hiding, to provide rapid encryption and de
cryption. It is shown that DNA steganography based on DNA binary strands is
secure under the assumption that an interceptor has the same technological
capabilities as sender and receiver of encrypted messages. The second appr
oach shown here is based on steganography and a method of graphical subtrac
tion of binary gel-images. II can be used to constitute a molecular checksu
m and can be combined with the first approach to support encryption. DNA cr
yptography might become of practical relevance in the context of labelling
organic and inorganic materials with DNA 'barcodes'. (C) 2000 Elsevier Scie
nce Ireland Ltd. All rights reserved.