The effects of needle bevel orientation and cerebrospinal fluid (CSF) press
ure on dural displacement and force required to penetrate cadaveric dura we
re studied using 40 samples. A constant hydrostatic pressure was applied to
the subdural surface, either high or low, simulating the sitting and later
al positions. A 17-gauge Tuohy needle was advanced through the dura with th
e bevel oriented parallel or perpendicular to dural fibres. Travel distance
and peak force at which dural penetration occurred were measured under bot
h pressure conditions. The work required to produce dural penetration was c
alculated. Greater force and work were required to penetrate dura in the pe
rpendicular orientation (P<0.05), regardless of the subdural pressure exert
ed. Dural displacement was similar under both pressure conditions.