Proteomics: the industrialization of protein chemistry

Authors
Citation
Sd. Patterson, Proteomics: the industrialization of protein chemistry, CURR OPIN B, 11(4), 2000, pp. 413-418
Citations number
47
Categorie Soggetti
Microbiology
Journal title
CURRENT OPINION IN BIOTECHNOLOGY
ISSN journal
09581669 → ACNP
Volume
11
Issue
4
Year of publication
2000
Pages
413 - 418
Database
ISI
SICI code
0958-1669(200008)11:4<413:PTIOPC>2.0.ZU;2-#
Abstract
Establishing a proteomics platform in the industrial setting initially requ ired implementation of a series of robotic systems to allow a high-throughp ut approach to analysis and identification of differences observed on 2-D e lectrophoresis gels. Now, a simpler alternative approach employing chromato graphy-based systems is emerging for identification of many components of c omplex mixtures, which can also provide quantitative comparisons through th e use of a new labeling methodology.