The idea that sensory information is represented by the temporal firing pat
terns of neurons or entire networks, rather than by firing rates measured o
ver long integration times, has recently gained increasing experimental sup
port. A number of mechanisms that help to preserve temporal information in
ascending sensory systems have been identified, and the role of inhibition
in these processes has been characterized. Furthermore, it has become obvio
us that temporal processing and the representation of sensory events by tem
poral spike patterns are highly dependent upon the behavioral state of the
animal or experimental subject.