Communication theory and techniques, aided by the electronic revolution, pr
ovide new opportunities and challenges for the effective transfer of labora
tory, epidemiologic, surveillance, and other public health data to the publ
ic who funds them. We review the applicability of communication theory, par
ticularly the audience-source-message-channel meta-model, to emerging infec
tious disease issues. Emergence of new infectious organisms, microbial resi
stance to therapeutic drugs, and increased emphasis on prevention have expa
nded the role of communication as a vital component of public health practi
ce. In the absence of cure, as in AIDS and many other public health problem
s, an effectively crafted and disseminated prevention message is the key co
ntrol measure. Applying communication theory to disease prevention messages
can increase the effectiveness of the messages and improve public health.