A new method for the reliable assessment of testicular core temperature usi
ng microwave technology is presented. This study was designed to assess whe
ther alterations in testicular thermoregulation could be reliably demonstra
ted in patients with clinically apparent varicoceles (n = 36), in those wit
h idiopathic male infertility (n = 52) and in fertile donors (n = 20) using
this new microwave thermographic technique. The measurements obtained were
found to be reliable and reproducible, Testicular core temperature measure
ments were significantly different between the groups (P < 0.001). Furtherm
ore, there was a temperature gradient between the scrotal neck and the test
icular core in all groups; testicular core temperatures were lower than scr
otal neck temperatures, The magnitude of this temperature difference was al
so significantly different (P < 0.001) between the groups. Microwave testic
ular thermography is a new technique that is safe and accurate, Preliminary
results suggest altered testicular thermoregulation in a group of patients
with impaired spermatogenesis with and without varicocele, Testicular temp
erature profiles obtained by microwave thermography may be of value in the
assessment of infertile men with or without a varicocele.