LACTOGENIC RECEPTORS ON BOVINE GRANULOSA-CELLS

The dependence of binding of bovine prolactin by bovine granulosa cell s on the diameter of antral follicles was investigated. The data sugge st that granulosa cells express one population of low-affinity prolact in binding sites. There was no significant change in the parameters of interaction of bovine prolactin with lactogenic binding sites during folliculogenesis. Recombinant bovine somatotropic hormone and bovine p rolactin compete for binding to the lactogenic binding sites, suggesti ng that the effects of both hormones can be mediated by the same bindi ng sites on bovine granulosa cells.