Lactoferrin and eosinophilic cationic protein in nasal secretions of patients with experimental rhinovirus colds, natural colds, and presumed acute community-acquired bacterial sinusitis

Authors
Niehaus, MD Gwaltney, JM Hendley, JO Newman, MJ Heymann, PW Rakes, GP Platts-Mills, TAE Guerrant, RL
Citation
Md. Niehaus et al., Lactoferrin and eosinophilic cationic protein in nasal secretions of patients with experimental rhinovirus colds, natural colds, and presumed acute community-acquired bacterial sinusitis, J CLIN MICR, 38(8), 2000, pp. 3100-3102
Citations number
18
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
00951137 → ACNP
Volume
38
Issue
8
Year of publication
2000
Pages
3100 - 3102
Database
ISI
SICI code
0095-1137(200008)38:8<3100:LAECPI>2.0.ZU;2-7
Abstract
To distinguish sinusitis from uncomplicated "colds," we examined lactoferri n and eosinophilic cationic protein (ECP) in nasal secretions. Lactoferrin titers were greater than or equal to 1:400 in 4% of persons with uncomplica ted colds and controls but in 79% of persons with sinusitis or purulent spu ta. ECP levels were >200 ng/ml in 61% of persons with colds and >3,000 ng/m l in 62% of persons with sinusitis. Nasal lactoferrin helps distinguish sin usitis from colds.