Immunohistochemical detection of steroid receptors in breast cancer: a working protocol

Authors
Leake, R Barnes, D Pinder, S Ellis, I Anderson, L Anderson, T Adamson, R Rhodes, T Miller, I Walker, R
Citation
R. Leake et al., Immunohistochemical detection of steroid receptors in breast cancer: a working protocol, J CLIN PATH, 53(8), 2000, pp. 634-635
Citations number
4
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
Journal title
JOURNAL OF CLINICAL PATHOLOGY
ISSN journal
00219746 → ACNP
Volume
53
Issue
8
Year of publication
2000
Pages
634 - 635
Database
ISI
SICI code
0021-9746(200008)53:8<634:IDOSRI>2.0.ZU;2-O
Abstract
The biochemical assay for the oestrogen receptor has shown the clinical val ue of knowing the concentration of the receptor within tissue. The immunohi stochemical assay is rapidly taking over from the biochemical assay. Theref ore, it is vital to have an equivalent scoring system that will have the sa me predictive value. This paper reports both a practical protocol and a sco ring system that should achieve this aim. This approach should be applicabl e to many more biomarkers detected by immunohistochemistry.