Response time prolongation for a motion stimulus in patients with glaucomaand its relationship with elevation of the motion threshold

Purpose: To investigate whether response times for a motion stimulus are pr olonged in glaucoma and to investigate the relationship between response ti me prolongation and motion threshold elevation in glaucoma. Method: Motion displacement thresholds and response times were measured in 15 patients with glaucoma and 18 age-matched control subjects. Results: Mean test response times were significantly prolonged in the glauc omatous eyes than in the control eyes, with a mean delay of 200 millisecond s. After correcting for threshold elevation, response times at the motion t hreshold showed no significant difference between the groups. Conclusions: Response times for motion detection are significantly prolonge d in glaucoma and are accounted for by the threshold elevation in patients with glaucoma. The implications of these results are discussed in terms of the use of response time analysis to determine subject reliability.