POSSIBLE USE OF CARBON ENTEROSORBENTS FOR NORMALIZING CHOLESTEROL-METABOLISM

The kinetics of adsorption of bile acids and cholesterol from biologic al fluids (bile) and reference solutions on SCN carbon and conventiona l medical carbon were compared with respect to their role as sorbents in normalizing cholesterol metabolism. The adsorptive capacity of carb on sorbents is primarily determined by their porous structure and also by the chemical properties of the adsorbing surface. The enterosorben ts were tested in both experimental animals and in clinical trials and are now successfully employed for preventing and treatment of atheros clerosis and for normalizing lipid metabolism. A procedure for surgica l treatment combined with adsorptive detoxication (enterosorption) was developed and introduced in clinical practice for patients with obstr uctive jaundice.